| Substance |
Info | Dose |
Warn | Link |
PubMed |
Latest article |
| Melatonin | 📋 | ✍ | ⛔ | | 38500787 | Melatonin at repeated doses alleviates hyperglycemia-exacerbated cerebral ischemia-reperfusion injury at 72 h via anti-inflammation and anti-apoptosis |
| Ginsenosides | 📋 | ✍ | ⛔ | | 38705107 | Synergistic promotion of angiogenesis after intracerebral hemorrhage by ginsenoside Rh2 and chrysophanol in rats |
| Curcumin | 📋 | ✍ | ⛔ | | 38082237 | The effects of curcumin-piperine supplementation on inflammatory, oxidative stress and metabolic indices in patients with ischemic stroke in the rehabilitation phase: a randomized controlled trial |
| Astragalosides | 📋 | ✍ | ⛔ | | 38621909 | [Mechanism of astragaloside â…£ combined with Panax notoginseng saponins in regulating angiogenesis to treat cerebral ischemia based on network pharmacology and experimental verification] |
| Resveratrol | 📋 | ✍ | ⛔ | | 38326707 | Long-Term Resveratrol Intake for Cognitive and Cerebral Blood Flow Impairment in Carotid Artery Stenosis/Occlusion |
| Ginkgo Biloba | 📋 | ✍ | ⛔ | | 38519277 | Chinese herbal medicine Ginkgo biloba L. preparations for ischemic stroke: An overview of systematic reviews and meta-analyses |
| Berberine | 📋 | ✍ | ⛔ | | 38639436 | Atorvastatin-induced intracerebral hemorrhage is inhibited by berberine in zebrafish |
| Ginkgolides | 📋 | | | | 37532074 | Ginkgolide B attenuates cerebral ischemia-reperfusion injury via inhibition of ferroptosis through disrupting NCOA4-FTH1 interaction |
| Citicoline | 📋 | ✍ | ⛔ | | 37812361 | The Combination of Citicoline and Nicotinamide Mononucleotide Induces Neurite Outgrowth and Mitigates Vascular Cognitive Impairment via SIRT1/CREB Pathway |
| Ginseng | 📋 | ✍ | ⛔ | | 38699996 | Panax notoginseng Saponins Activate Nuclear Factor Erythroid 2-Related Factor 2 to Inhibit Ferroptosis and Attenuate Inflammatory Injury in Cerebral Ischemia-Reperfusion |
| Cannabidiol | 📋 | ✍ | ⛔ | | 37841923 | Anti-oxidant effects of cannabidiol relevant to intracerebral hemorrhage |
| Vitamin D3 | 📋 | ✍ | ⛔ | | 38347057 | The relationship between the level of vitamin D and ruptured intracranial aneurysms among patients with high sun exposure |
| Salidroside | 📋 | | | | 38643543 | Salidroside promotes angiogenesis after cerebral ischemia in mice through Shh signaling pathway |
| Magnesium | 📋 | ✍ | ⛔ | | 38514031 | Early intravenous magnesium sulfate and its impact on cerebral vasospasm as well as delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage: A retrospective matched case-control analysis |
| Quercetin | 📋 | ✍ | ⛔ | | 38571617 | Quercetin attenuated ischemic stroke induced neurodegeneration by modulating glutamatergic and synaptic signaling pathways |
| Salvianolic Acid | 📋 | | | | 38468280 | Salvianolic acid C attenuates cerebral ischemic injury through inhibiting neuroinflammation via the TLR4-TREM1-NF-κB pathway |
| Puerarin | 📋 | ✍ | ⛔ | | 38114205 | [Research progress in mechanism of puerarin in treating vascular dementia] |
| EGCG | 📋 | ✍ | ⛔ | | 38427657 | Epigallocatechin gallate improves neuronal damage in animal model of ischemic stroke and glutamate-exposed neurons via modulation of hippocalcin expression |
| Astaxanthin | 📋 | ✍ | ⛔ | | 35447940 | Astaxanthin Confers a Significant Attenuation of Hippocampal Neuronal Loss Induced by Severe Ischemia-Reperfusion Injury in Gerbils by Reducing Oxidative Stress |
| Baicalin | 📋 | ✍ | ⛔ | | 38631145 | Upregulation of Nrf2 signaling: A key molecular mechanism of Baicalin's neuroprotective action against diabetes-induced cognitive impairment |
| Metformin | 📋 | ✍ | ⛔ | | 38043334 | Neuroprotective effects of oral metformin before stroke on cerebral small-vessel disease |
| Astragalus Root | 📋 | ✍ | ⛔ | | 38588987 | Mechanism of Astragalus mongholicus Bunge ameliorating cerebral ischemia-reperfusion injury: Based on network pharmacology analysis and experimental verification |
| Luteolin | 📋 | ✍ | ⛔ | | 35778706 | Luteolin alleviates inflammation and autophagy of hippocampus induced by cerebral ischemia/reperfusion by activating PPAR gamma in rats |
| NMN | 📋 | ✍ | ⛔ | | 37812361 | The Combination of Citicoline and Nicotinamide Mononucleotide Induces Neurite Outgrowth and Mitigates Vascular Cognitive Impairment via SIRT1/CREB Pathway |
| Pterostilbene | 📋 | ✍ | ⛔ | | 37614235 | Pterostilbene attenuates microglial inflammation and brain injury after intracerebral hemorrhage in an OPA1-dependent manner |
| Sulforaphane | 📋 | ✍ | ⛔ | | 36244590 | Sulforaphane promotes white matter plasticity and improves long-term neurological outcomes after ischemic stroke via the Nrf2 pathway |
| Goji Berry | 📋 | ✍ | ⛔ | | 36866558 | Lycium barbarum Ameliorates Neural Damage Induced by Experimental Ischemic Stroke and Radiation Exposure |
| Ligustilide | 📋 | | | | 36017237 | Ligustilide Improves Cognitive Impairment via Regulating the SIRT1/IRE1 α/XBP1s/CHOP Pathway in Vascular Dementia Rats |
| Selenium | 📋 | ✍ | ⛔ | | 38707461 | Prophylactic zinc and therapeutic selenium administration in adult rats prevents long-term cognitive and behavioral sequelae by a transient ischemic attack |
| Andrographolide | 📋 | | | | 35602108 | URB597 and Andrographolide Improve Brain Microvascular Endothelial Cell Permeability and Apoptosis by Reducing Oxidative Stress and Inflammation Associated with Activation of Nrf2 Signaling in Oxygen-Glucose Deprivation |
| Baicalein | 📋 | ✍ | ⛔ | | 38295883 | Baicalein ameliorates cognitive impairment of vascular dementia rats via suppressing neuroinflammation and regulating intestinal microbiota |
| Chlorogenic Acid | 📋 | ✍ | ⛔ | | 38429854 | Chlorogenic acid regulates the expression of protein phosphatase 2A subunit B in the cerebral cortex of a rat stroke model and glutamate-exposed neurons |
| Chrysin | 📋 | ✍ | ⛔ | | 38555815 | Chrysin inhibits ferroptosis of cerebral ischemia/reperfusion injury via regulating HIF-1α/CP loop |
| CoQ10 | 📋 | ✍ | ⛔ | | 38627309 | Coenzyme Q10 and exercise training reinstate middle cerebral artery occlusion-induced behavioral deficits and hippocampal long-term potentiation suppression in aging rats |
| Omega-3 Fatty Acids | 📋 | ✍ | ⛔ | | 38134264 | Omega-3 Blood Levels and Stroke Risk: A Pooled and Harmonized Analysis of 183 291 Participants From 29 Prospective Studies |
| Vitamin B12 | 📋 | ✍ | ⛔ | | 38715940 | Functional regulation of microglia by vitamin B12 alleviates ischemic stroke-induced neuroinflammation in mice |
| Acetyl-L-Carnitine | 📋 | ✍ | ⛔ | | 38155210 | Investigation of the effect of carnitine on cerebral vasospasm in experimental subarachnoid hemorrhage model |
| Crocin | 📋 | ✍ | ⛔ | | 35991882 | Crocins for Ischemic Stroke: A Review of Current Evidence |
| Dihydromyricetin | 📋 | ✍ | ⛔ | | 37603215 | Dihydromyricetin Alleviates Ischemic Brain Injury by Antagonizing Pyroptosis in Rats |
| Fisetin | 📋 | ✍ | ⛔ | | 38452414 | Fisetin alleviates cerebral ischemia/reperfusion injury by regulating Sirt1/Foxc1/Ubqln1 pathway-mediated proteostasis |
| Geniposide | 📋 | | | | 38402902 | Geniposide ameliorates brain injury in mice with intracerebral hemorrhage by inhibiting NF-κB signaling |
| Genistein | 📋 | ✍ | ⛔ | | 36690381 | Beneficial effects of the phytoestrogen genistein on hippocampal impairments of spontaneously hypertensive rats (SHR) |
| Tanshinone | 📋 | | | | 38549714 | Tanshinone IIA Alleviates Traumatic Brain Injury by Reducing Ischemia‒Reperfusion via the miR-124-5p/FoxO1 Axis |
| Vitamin B9 | 📋 | ✍ | ⛔ | | 38432716 | Dosage exploration of combined B-vitamin supplementation in stroke prevention: a meta-analysis and systematic review |
| Bilobalide | 📋 | | | | 31864312 | The neuroprotective mechanisms of ginkgolides and bilobalide in cerebral ischemic injury: a literature review |
| Docosahexaenoic Acid | 📋 | ✍ | ⛔ | | 38676880 | Omega-3 Fatty Acids and Risk of Ischemic Stroke in REGARDS |
| Green Tea | 📋 | ✍ | ⛔ | | 38308353 | Green tea consumption and incidence of cardiovascular disease in type 2 diabetic patients with overweight/obesity: a community-based cohort study |
| Thymoquinone | 📋 | | ⛔ | | 38325603 | Thymoquinone regulates microglial M1/M2 polarization after cerebral ischemia-reperfusion injury via the TLR4 signaling pathway |
| Vitamin C | 📋 | ✍ | ⛔ | | 35911106 | Vitamin C Intake and Ischemic Stroke |
| Apigenin | 📋 | ✍ | ⛔ | | 36314275 | |Therapeutic and preventive effects of apigenin in cerebral ischemia: a review |
| Icariin | 📋 | ✍ | | | 38706972 | Icariin inhibits apoptosis in OGD-induced neurons by regulating M2 pyruvate kinase |
| Catalpol | 📋 | | | | 38522312 | Catalpol attenuates ischemic stroke by promoting neurogenesis and angiogenesis via the SDF-1α/CXCR4 pathway |
| L-Carnosine | 📋 | ✍ | ⛔ | | 36906993 | Neuroprotective effects of carnosine in a mice stroke model concerning oxidative stress and inflammatory response |
| Naringin | 📋 | ✍ | ⛔ | | 38457013 | Effect of 2-Week Naringin Supplementation on Neurogenesis and BDNF Levels in Ischemia-Reperfusion Model of Rats |
| Rapamycin | 📋 | ✍ | | | 38224443 | Rapamycin Alleviates Neuronal Injury and Modulates Microglial Activation After Cerebral Ischemia |
| Red Sage | 📋 | ✍ | ⛔ | | 38036060 | Uncovering Mechanism and Efficacy of Salvia Miltiorrhiza-Safflower in Cerebral Ischemia-Reperfusion Injury |
| Schisandrins | 📋 | | | | 38551405 | Effects of schisandrin B on hypoxia-related cognitive function and protein expression in vascular dementia rats |
| Scutellarin | 📋 | | | | 38219378 | Mechanism of scutellarin inhibition of astrocyte activation to type A1 after ischemic stroke |
| Allicin | 📋 | ✍ | ⛔ | | 37973218 | Therapeutic effect of allicin in a mouse model of intracerebral hemorrhage |
| Angelica | 📋 | ✍ | ⛔ | | 38731591 | Research Progress in Pharmacological Effects and Mechanisms of Angelica sinensis against Cardiovascular and Cerebrovascular Diseases |
| Artemisinin | 📋 | | | | 38454322 | Artemisinin ameliorates cognitive decline by inhibiting hippocampal neuronal ferroptosis via Nrf2 activation in T2DM mice |
| Ashwagandha | 📋 | ✍ | ⛔ | | 31870211 | Withanolide a penetrates brain via intra-nasal administration and exerts neuroprotection in cerebral ischemia reperfusion injury in mice |
| Aspirin | 📋 | | ⛔ | | 38039031 | Comprehensive systematic review and meta-analysis on anticoagulants and aspirin for stroke prevention in non-valvular atrial fibrillation patients |
| Boswellic Acid | 📋 | ✍ | ⛔ | | 37230158 | Novel synergistic mechanism of 11-keto-β-boswellic acid and Z-Guggulsterone on ischemic stroke revealed by single-cell transcriptomics |
| Dihydroquercetin | 📋 | | | | 37511195 | A Comparative Analysis of Neuroprotective Properties of Taxifolin and Its Water-Soluble Form in Ischemia of Cerebral Cortical Cells of the Mouse |
| Eicosapentaenoic Acid | 📋 | ✍ | ⛔ | | 38680120 | Eicosapentaenoic acid activates the P62/KEAP1/NRF2 pathway for the prevention of diabetes-associated cognitive dysfunction |
| Fucoidan | 📋 | ✍ | ⛔ | | 38237671 | Fucoidan protects CA1 pyramidal neurons of the hippocampus and preserves the cognitive profile of rats subjected to transient forebrain ischemia |
| Gingerol | 📋 | ✍ | | | 38665422 | In vivo protective effects of 6‑gingerol in cerebral ischemia involve preservation of antioxidant defenses and activation of anti‑apoptotic pathways |
| Icaritin | 📋 | | | | 36643627 | UHPLC-ESI-QE-Orbitrap-MS based metabolomics reveals the antioxidant mechanism of icaritin on mice with cerebral ischemic reperfusion |
| Kaempferol | 📋 | ✍ | ⛔ | | 38585626 | Kaempferol regulates apoptosis and migration of neural stem cells to attenuate cerebral infarction by O-GlcNAcylation of β-catenin |
| Phytochemicals | 📋 | | | | 36289828 | A Review on Therapeutic Potential of Natural Phytocompounds for Stroke |
| Saffron | 📋 | ✍ | ⛔ | | 36302045 | Ameliorative effects of half-dose saffron and chamomile combination on Psycho-endocrinological changes in a diabetic murine model |
| Tribulus Terrestris | 📋 | ✍ | ⛔ | | 37876150 | Dietary Supplement with Tribulus terrestris L. Extract Exhibits Protective Effects on Ischemic Stroke Rats |
| TUDCA | 📋 | ✍ | ⛔ | | 33261652 | Tauroursodeoxycholic acid attenuates neuronal apoptosis via the TGR5/ SIRT3 pathway after subarachnoid hemorrhage in rats |
| Calycosin | 📋 | | | | 37528661 | Calycosin attenuates the inflammatory damage of microglia induced by oxygen and glucose deprivation through the HMGB1/TLR4/NF-κB signaling pathway |
| Fo-Ti Root | 📋 | ✍ | ⛔ | | 38623977 | Exploring the Constituents and Mechanisms of Polygonum multiflorum Thunb. in Mitigating Ischemic Stroke: A Network Pharmacology and Molecular Docking Study |
| Ginkgetin | 📋 | | | | 35593977 | Ginkgetin Promotes M2 Polarization of Microglia and Exert Neuroprotection in Ischemic Stroke via Modulation of PPARγ Pathway |
| Lipoic Acid | 📋 | ✍ | ⛔ | | 38305103 | Alpha-lipoic acid (ALA) ameliorates early brain injury after subarachnoid hemorrhage in Sprague-Dawley (SD) rats via inhibiting STING-NLRP3 inflammatory signaling |
| Nobiletin | 📋 | ✍ | | | 36660614 | Neuroprotective effects of nobiletin on cerebral ischemia/reperfusion injury rats by inhibiting Rho/ROCK signaling pathway |
| Ollive Leaf extract | 📋 | ✍ | ⛔ | | 38153337 | Expression of Na+/Ca2+ exchangers were enhanced following pre-treatment of olive leaf extract and olive oil in animal model of ischemic stroke |
| Pine Bark | 📋 | ✍ | ⛔ | | 36992594 | Therapeutic Treatment with Pycnogenol® Attenuates Ischemic Brain Injury in Gerbils Focusing on Cognitive Impairment, Neuronal Death, BBB Leakage and Neuroinflammation in the Hippocampus |
| Urolithins | 📋 | | | | 38360072 | Intestinal metabolite UroB alleviates cerebral ischemia/reperfusion injury by promoting competition between TRIM65 and TXNIP for binding to NLRP3 inflammasome in response to neuroinflammation |
| Aged Garlic | 📋 | ✍ | ⛔ | | 31851788 | Aged garlic extract and S-allylcysteine increase the GLUT3 and GCLC expression levels in cerebral ischemia |
| Caffeine | 📋 | ✍ | ⛔ | | 36577880 | Caffeine protects against hippocampal alterations in type 2 diabetic rats via modulation of gliosis, inflammation and apoptosis |
| Capsaicin | 📋 | ✍ | ⛔ | | 36986266 | Capsaicin: A Potential Treatment to Improve Cerebrovascular Function and Cognition in Obesity and Ageing |
| Daidzein | 📋 | ✍ | ⛔ | | 35095491 | Neuroprotective Effect of Daidzein Extracted From Pueraria lobate Radix in a Stroke Model Via the Akt/mTOR/BDNF Channel |
| Ellagic Acid | 📋 | ✍ | ⛔ | | 38106628 | Ellagic acid alleviates motor, cognitive and hippocampal electrical activity deficits in the male rats with 2-vessel occlusion cerebral ischemia/reperfusion |
| Escin | 📋 | ✍ | ⛔ | | 37716034 | Escin avoids hemorrhagic transformation in ischemic stroke by protecting BBB through the AMPK/Cav-1/MMP-9 pathway |
| Folate | 📋 | ✍ | ⛔ | | 37456629 | Associations between homocysteine and B vitamins and stroke: a cross-sectional study |
| Formononetin | 📋 | | | | 38452845 | Formononetin alleviates cerebral ischemia-reperfusion injury in rats by targeting the PARP-1/PARG/Iduna signaling pathway |
| Galangin | 📋 | | | | 33127512 | Galangin attenuated cerebral ischemia-reperfusion injury by inhibition of ferroptosis through activating the SLC7A11/GPX4 axis in gerbils |
| Gallic Acid | 📋 | | ⛔ | | 37222948 | Effects of Gallic Acid on Memory Deficits and Electrophysiological Impairments Induced by Cerebral Ischemia/Reperfusion in Rats Following Exposure to Ambient Dust Storm |
| Grape Seed extract | 📋 | ✍ | ⛔ | | 33485068 | Protective effect of grape seed extract and orlistat co-treatment against stroke: Effect on oxidative stress and energy failure |
| Horny Goat Weed | 📋 | ✍ | ⛔ | | 37237865 | Epimedium Aqueous Extract Ameliorates Cerebral Ischemia/Reperfusion Injury through Inhibiting ROS/NLRP3-Mediated Pyroptosis |
| Mangiferin | 📋 | | ⛔ | | 36322276 | Mangiferin exerts neuroprotective effects against focal cerebral ischemia in mice by regulating NF-κB signaling pathway |
| N-Acetyl Cysteine | 📋 | ✍ | ⛔ | | 38004075 | An Evaluation of the Effectiveness of Melatonin and n-Acetylcysteine in Cerebral Ischemia-Reperfusion Injury in Adult Rats |
| Naringenin | 📋 | ✍ | ⛔ | | 38141009 | Naringenin alleviates cognitive dysfunction in rats with cerebral ischemia/reperfusion injury through up-regulating hippocampal BDNF-TrkB signaling: involving suppression in neuroinflammation and oxidative stress |
| Neferine | 📋 | | | | 38428144 | Nrf2 activation by neferine mitigates microglial neuroinflammation after subarachnoid hemorrhage through inhibiting TAK1-NF-κB signaling |
| Paeoniflorin | 📋 | | | | 38178130 | Combination of Atractylenolide I, Atractylenolide III, and Paeoniflorin promotes angiogenesis and improves neurological recovery in a mouse model of ischemic Stroke |
| Piperine | 📋 | ✍ | ⛔ | | 38082237 | The effects of curcumin-piperine supplementation on inflammatory, oxidative stress and metabolic indices in patients with ischemic stroke in the rehabilitation phase: a randomized controlled trial |
| Polyphenols | 📋 | | | | 36904106 | Polyphenols Mediate Neuroprotection in Cerebral Ischemic Stroke-An Update |
| Pomegranate | 📋 | | ⛔ | | 30834085 | Methanolic leaf extract of Punica granatum attenuates ischemia-reperfusion brain injury in Wistar rats: Potential antioxidant and anti-inflammatory mechanisms |
| Pomegranate Seed extract | 📋 | | ⛔ | | 26031017 | Motor and cognitive deficits due to permanent cerebral hypoperfusion/ischemia improve by pomegranate seed extract in rats |
| Rutin | 📋 | ✍ | ⛔ | | 37414348 | Lithium Co-administration with rutin improves post-stroke neurological outcomes via suppressing Gsk-3β activity in a rat model |
| Taurine | 📋 | ✍ | ⛔ | | 38616233 | Taurine ameliorates sensorimotor function by inhibiting apoptosis and activating A2 astrocytes in mice after subarachnoid hemorrhage |
| Trehalose | 📋 | | ⛔ | | 35647904 | Preconditioning with Trehalose Protects the Bone Marrow-Derived Mesenchymal Stem Cells Under Oxidative Stress and Enhances the Stem Cell-Based Therapy for Cerebral Ischemic Stroke |
| Vitamin E | 📋 | ✍ | ⛔ | | 35082970 | Diet-Derived Circulating Antioxidants and Risk of Stroke: A Mendelian Randomization Study |
| Wogonin | 📋 | ✍ | ⛔ | | 38253131 | Wogonin alleviates NLRP3 inflammasome activation after cerebral ischemia-reperfusion injury by regulating AMPK/SIRT1 |
| Zinc | 📋 | ✍ | ⛔ | | 38707461 | Prophylactic zinc and therapeutic selenium administration in adult rats prevents long-term cognitive and behavioral sequelae by a transient ischemic attack |
| Aloe-Emodin | 📋 | | | | 38621328 | Aloe-emodin alleviates cerebral ischemia-reperfusion injury by regulating microglial polarization and pyroptosis through inhibition of NLRP3 inflammasome activation |
| Antioxidants | 📋 | | ⛔ | | 38540114 | Novel Multi-Antioxidant Approach for Ischemic Stroke Therapy Targeting the Role of Oxidative Stress |
| Arctigenin | 📋 | | | | 28888980 | Arctigenin attenuates ischemic stroke via SIRT1-dependent inhibition of NLRP3 inflammasome |
| Cinnamon | 📋 | ✍ | ⛔ | | 36577044 | Protective effects of cinnamon on acetylcholinesterase activity and memory dysfunction in diabetic rats |
| Cocoa | 📋 | ✍ | ⛔ | | 31236643 | The effect of acute cocoa flavanol intake on the BOLD response and cognitive function in type 1 diabetes: a randomized, placebo-controlled, double-blinded cross-over pilot study |
| Coffee | 📋 | ✍ | ⛔ | | 38714417 | Coffee and tea consumption and dementia risk: The role of sex and vascular comorbidities |
| Emodin | 📋 | | ⛔ | | 37380800 | Brain-Targeting Emodin Mitigates Ischemic Stroke via Inhibiting AQP4-Mediated Swelling and Neuroinflammation |
| Ferulic Acid | 📋 | ✍ | ⛔ | | 37927604 | Efficacy of ferulic acid in the treatment of acute ischemic stroke injury in rats: a systematic review and meta-analysis |
| Fish | 📋 | | ⛔ | | 38676880 | Omega-3 Fatty Acids and Risk of Ischemic Stroke in REGARDS |
| Food | 📋 | | | | 38397735 | Neuroprotection Afforded by an Enriched Mediterranean-like Diet Is Modified by Exercise in a Rat Male Model of Cerebral Ischemia |
| Frankincense | 📋 | ✍ | ⛔ | | 35082676 | Combination of Systems Pharmacology and Experimental Evaluation to Explore the Mechanism of Synergistic Action of Frankincense-Myrrh in the Treatment of Cerebrovascular Diseases |
| Glucosamine | 📋 | ✍ | ⛔ | | 37689747 | Habitual glucosamine use, APOE genotypes, and risk of incident cause-specific dementia in the older population |
| Hesperidin | 📋 | ✍ | ⛔ | | 31478148 | Hesperidin reduces adverse symptomatic intracerebral hemorrhage by promoting TGF-β1 for treating ischemic stroke using tissue plasminogen activator |
| Honokiol | 📋 | | | | 37481555 | SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes |
| Linoleic Acid | 📋 | ✍ | ⛔ | | 33584789 | Association Between Circulating Linoleic Acid and Risk of Ischemic Stroke |
| Long Pepper | 📋 | | ⛔ | | 37821784 | The extract of Sclerocarya birrea, Nauclea latifolia, and Piper longum mixture ameliorates diabetes-associated cognitive dysfunction |
| Lycopene | 📋 | ✍ | ⛔ | | 34284544 | Lycopene supplementation protects vascular dementia gerbils against the impairment of learning and memory |
| Medicinal Plants | 📋 | | | | 35928282 | An Update on the Potential Application of Herbal Medicine in Promoting Angiogenesis |
| Modified Citrus Pectin | 📋 | ✍ | ⛔ | | 35706530 | Modified Citrus Pectin Alleviates Cerebral Ischemia/Reperfusion Injury by Inhibiting NLRP3 Inflammasome Activation via TLR4/NF-ĸB Signaling Pathway in Microglia |
| Nicotinamide Riboside | 📋 | ✍ | ⛔ | | 38723719 | Nicotinamide riboside alleviates brain dysfunction induced by chronic cerebral hypoperfusion via protecting mitochondria |
| Nigella Sativa | 📋 | ✍ | ⛔ | | 37038292 | Potential role of Nigella Sativa and its Constituent (Thymoquinone) in Ischemic Stroke |
| Nuciferine | 📋 | | | | 38232541 | Nuciferine reduces inflammation induced by cerebral ischemia-reperfusion injury through the PI3K/Akt/NF-κB pathway |
| Olive Oil | 📋 | ✍ | ⛔ | | 38153337 | Expression of Na+/Ca2+ exchangers were enhanced following pre-treatment of olive leaf extract and olive oil in animal model of ischemic stroke |
| Peony | 📋 | | ⛔ | | 37172921 | Paeoniae Radix Rubra extract attenuates cerebral ischemia injury by inhibiting ferroptosis and activating autophagy through the PI3K/Akt signalling pathway |
| Retinoic Acid | 📋 | | | | 37149281 | Retinoic acid has neuroprotective effects by modulating thioredoxin in ischemic brain damage and glutamate-exposed neurons |
| Safflower | 📋 | ✍ | ⛔ | | 38036060 | Uncovering Mechanism and Efficacy of Salvia Miltiorrhiza-Safflower in Cerebral Ischemia-Reperfusion Injury |
| Stinging Nettle | 📋 | ✍ | ⛔ | | 33839493 | Exercise and Urtica dioica extract ameliorate hippocampal insulin signaling, oxidative stress, neuroinflammation, and cognitive function in STZ-induced diabetic rats |
| Tangeretin | 📋 | | | | 38074289 | Tangeretin confers neuroprotection, cognitive and memory enhancement in global cerebral ischemia in rats |
| Tea | 📋 | | | | 38714417 | Coffee and tea consumption and dementia risk: The role of sex and vascular comorbidities |
| Vitamin B6 | 📋 | ✍ | ⛔ | | 38432716 | Dosage exploration of combined B-vitamin supplementation in stroke prevention: a meta-analysis and systematic review |
| Vitexin | 📋 | | | | 36435955 | Vitexin Improves Cerebral ischemia‑reperfusion Injury by Attenuating Oxidative Injury and Ferroptosis via Keap1/Nrf2/HO-1signaling |
| Asiatic Acid | 📋 | | | | 25087961 | Neuroprotective effect of asiatic acid in rat model of focal embolic stroke |
| Asiaticoside | 📋 | | | | 32006420 | Asiaticoside Alleviates Cerebral Ischemia-Reperfusion Injury via NOD2/Mitogen-Activated Protein Kinase (MAPK)/Nuclear Factor kappa B (NF-κB) Signaling Pathway |
| Atractylodes | 📋 | ✍ | ⛔ | | 38178130 | Combination of Atractylenolide I, Atractylenolide III, and Paeoniflorin promotes angiogenesis and improves neurological recovery in a mouse model of ischemic Stroke |
| Bee Propolis | 📋 | ✍ | ⛔ | | 33322707 | The Role of Mitochondria in Brain Cell Protection from Ischaemia by Differently Prepared Propolis Extracts |
| Beta-Carotene | 📋 | ✍ | ⛔ | | 36552554 | Protective Effect of Beta-Carotene against Myeloperoxidase- Mediated Oxidative Stress and Inflammation in Rat Ischemic Brain Injury |
| Black Pepper | 📋 | ✍ | ⛔ | | 36435434 | Effects of dichloromethane extraction from Piper nigrum L. and P. longum L. on the expression of autophagy-related proteins in ischemic stroke |
| Burdock | 📋 | | ⛔ | | 38669967 | Ethanolic extract of Arctium lappa leaves alleviates cerebral ischemia reperfusion-induced inflammatory injury via HDAC9-mediated NF-κB pathway |
| Butyrate | 📋 | | ⛔ | | 38486971 | Protective effects of butyrate on cerebral ischaemic injury in animal models: a systematic review and meta-analysis |
| Caffeic Acid | 📋 | ✍ | ⛔ | | 37833536 | Caffeic acid alleviates cerebral ischemic injury in rats by resisting ferroptosis via Nrf2 signaling pathway |
| Calcium | 📋 | ✍ | ⛔ | | 35816459 | Calcium and magnesium in drinking water and risk of myocardial infarction and stroke - a population-based cohort study |
| Carvacrol | 📋 | ✍ | ⛔ | | 31729545 | Carvacrol suppresses learning and memory dysfunction and hippocampal damages caused by chronic cerebral hypoperfusion |
| Chrysanthemum | 📋 | ✍ | ⛔ | | 36567616 | Neuroprotective effects of Chrysanthemum morifolium on cerebral ischemia- reperfusion injury contributes to the oxidative stress suppression and related Keap1/Nrf2 pathway |
| Cordycepin | 📋 | | | | 35002628 | Cordycepin Ameliorates Synaptic Dysfunction and Dendrite Morphology Damage of Hippocampal CA1 via A1R in Cerebral Ischemia |
| Crocetin | 📋 | | | | 37001492 | Crocetin Regulates Functions of Neural Stem Cells to Generate New Neurons for Cerebral Ischemia Recovery |
| Diosgenin | 📋 | | | | 35217435 | Diosgenin revealed potential effect against cerebral ischemia reperfusion through HIKESHI/HSP70/NF-κB anti-inflammatory axis |
| Fish Oil | 📋 | ✍ | ⛔ | | 32756005 | Fish oil supplementation attenuates cognitive impairment by inhibiting neuroinflammation in STZ-induced diabetic rats |
| Flavonoids | 📋 | | ⛔ | | 38487170 | Novel insight into the therapeutical potential of flavonoids from traditional Chinese medicine against cerebral ischemia/reperfusion injury |
| Gardenia | 📋 | | ⛔ | | 36458485 | Gardenia jasminoides Extract GJ-4 Alleviates Memory Deficiency of Vascular Dementia in Rats through PERK-Mediated Endoplasmic Reticulum Stress Pathway |
| Geraniol | 📋 | | | | 38446318 | Geraniol attenuates oxygen-glucose deprivation/reoxygenation-induced ROS-dependent apoptosis and permeability of human brain microvascular endothelial cells by activating the Nrf-2/HO-1 pathway |
| Ginger | 📋 | ✍ | ⛔ | | 32802263 | Memory-Enhancing Effect of a Phytosome Containing the Combined Extract of Mulberry Fruit and Ginger in an Animal Model of Ischemic Stroke with Metabolic Syndrome |
| Glycyrrhizic Acid | 📋 | ✍ | ⛔ | | 32981927 | Ability of Post-treatment Glycyrrhizic Acid to Mitigate Cerebral Ischemia/Reperfusion Injury in Diabetic Mice |
| Gotu Kola | 📋 | ✍ | ⛔ | | 38428624 | Intermittent fasting along with hydroalcoholic extract of Centella-asiatica ameliorates sub-acute hypoxia-induced ischemic stroke in adult zebrafish |
| Holy Basil | 📋 | ✍ | ⛔ | | 37763282 | Ocimum sanctum Alters the Lipid Landscape of the Brain Cortex and Plasma to Ameliorate the Effect of Photothrombotic Stroke in a Mouse Model |
| Hydroxytyrosol | 📋 | | | | 34573155 | Extra Virgin Oil Polyphenols Improve the Protective Effects of Hydroxytyrosol in an In Vitro Model of Hypoxia-Reoxygenation of Rat Brain |
| Hyperoside | 📋 | | | | 37609123 | Vasoprotective Effects of Hyperoside against Cerebral Ischemia/Reperfusion Injury in Rats: Activation of Large-Conductance Ca2+-Activated K+ Channels |
| Isoliquiritigenin | 📋 | | | | 38395608 | Isoliquiritigenin attenuates neuroinflammation after subarachnoid hemorrhage through inhibition of NF-κB-mediated NLRP3 inflammasome activation |
| Isoquercitrin | 📋 | | | | 37391332 | Isoquercitrin Played a Neuroprotective Role in Rats After Cerebral Ischemia/Reperfusion Through Up-Regulating Neuroglobin and Anti-Oxidative Stress |
| L-Carnitine | 📋 | ✍ | ⛔ | | 32922474 | Evaluation of Neuroprtective Effects of L-Carnitine and Fat Emulsion in the CVA Patients: A Prospective, Randomized, Double Blind, Clinical Trial |
| Licorice Root | 📋 | ✍ | ⛔ | | 36559268 | Amelioration of Brain Damage after Treatment with the Methanolic Extract of Glycyrrhizae Radix et Rhizoma in Mice |
| Liquiritin | 📋 | | | | 34295249 | The Protective Effect of Liquiritin in Hypoxia/Reoxygenation-Induced Disruption on Blood Brain Barrier |
| Nattokinase | 📋 | ✍ | ⛔ | | 37466380 | Nattokinase Promotes Post-stroke Neurogenesis and Cognition Recovery via Increasing Circulating Irisin |
| Oleuropein | 📋 | | | | 32922228 | Oleuropein Improved Post Cerebral Stroke Cognitive Function by Promoting Histone Acetylation and Phosphorylation of cAMP Response Element-Binding Protein in MCAO Rats |
| PEA | 📋 | ✍ | ⛔ | | 35469820 | Palmitoylethanolamide ameliorates neuroinflammation via modulating PPAR-α to promote the functional outcome after intracerebral hemorrhage |
| Peanut | 📋 | | ⛔ | | 35418581 | Peanut (Arachis hypogaea) sprout prevents high-fat diet-induced cognitive impairment by improving mitochondrial function |
| Polydatin | 📋 | ✍ | | | 36915795 | Effects of polydatin from Huhuang Shaoshang Liniment on oxidative damage and inflammatory response in rats with cerebral ischemia-reperfusion |
| Pomelo | 📋 | | ⛔ | | 35571242 | Pomelo Peel Essential Oil Ameliorates Cerebral Ischemia-Reperfusion Injury through Regulating Redox Homeostasis in Rats and SH-SY5Y Cells |
| Potassium | 📋 | ✍ | ⛔ | | 28877896 | Intake of potassium- and magnesium-enriched salt improves functional outcome after stroke: a randomized, multicenter, double-blind controlled trial |
| Progesterone | 📋 | ✍ | ⛔ | | 38140038 | Neuroprotective-Neurorestorative Effects Induced by Progesterone on Global Cerebral Ischemia: A Narrative Review |
| Reishi Mushrooms | 📋 | ✍ | ⛔ | | 35088782 | Polysaccharide from Ganoderma lucidum alleviates cognitive impairment in a mouse model of chronic cerebral hypoperfusion by regulating CD4 + CD25 + Foxp3 + regulatory T cells |
| Rhubarb | 📋 | | ⛔ | | 38668344 | The Water Extract of Rhubarb Prevents Ischemic Stroke by Regulating Gut Bacteria and Metabolic Pathways |
| Rosmarinic Acid | 📋 | ✍ | | | 33548269 | Rosmarinic acid protects rats against post-stroke depression after transient focal cerebral ischemic injury through enhancing antioxidant response |
| Royal Jelly | 📋 | ✍ | ⛔ | | 38657030 | Comparative neuroprotective effects of royal jelly and its unique compound 10-hydroxy-2-decenoic acid on ischemia-induced inflammatory, apoptotic, epigenetic and genotoxic changes in a rat model of ischemic stroke |
| Silibinin | 📋 | ✍ | | | 37544575 | Silibinin exerts neuroprotective effects against cerebral hypoxia/reoxygenation injury by activating the GAS6/Axl pathway |
| Vitamin A | 📋 | ✍ | ⛔ | | 36004815 | Association of vitamin A and its organic compounds with stroke - a systematic review and meta-analysis |
| Vitamin K2 mk-4 | 📋 | ✍ | | | 38727984 | Menaquinone-4 Alleviates Neurological Deficits Associated with Intracerebral Hemorrhage by Preserving Corticospinal Tract in Mice |
| Wormwood | 📋 | ✍ | ⛔ | | 21999109 | Evaluation of antioxidant and free-radical scavenging potential of Artemisia absinthium |
| Acacetin | 📋 | | | | 38114218 | [Acacetin protects rats from cerebral ischemia-reperfusion injury by regulating TLR4/NLRP3 signaling pathway] |
| Acai Berry | 📋 | ✍ | ⛔ | | 36904206 | Oral Treatment with the Extract of Euterpe oleracea Mart. Improves Motor Dysfunction and Reduces Brain Injury in Rats Subjected to Ischemic Stroke |
| Alpha-Linolenic Acid | 📋 | ✍ | ⛔ | | 33915355 | Long-term dietary supplementation with plant-derived omega-3 fatty acid improves outcome in experimental ischemic stroke |
| Anthocyanins | 📋 | ✍ | ⛔ | | 30740157 | Balinese Cultivar of Purple Sweet Potato Improved Neurological Score and BDNF and Reduced Caspase-Independent Apoptosis Among Wistar Rats With Ischemic Stroke |
| BCAA | 📋 | ✍ | ⛔ | | 32689936 | Quick and effective improvement of leucine enriched dietary supplement on malnutrition in acute stroke patients receiving enteral tube feeding |
| Carnosol | 📋 | | | | 36775042 | Carnosol inhibits cerebral ischemia-reperfusion injury by promoting AMPK activation |
| Carotenoids | 📋 | ✍ | ⛔ | | 37502714 | The protective effect of serum carotenoids on cardiovascular disease: a cross-sectional study from the general US adult population |
| Coumaric acid | 📋 | | | | 33537297 | Alpinia oxyphylla Miq. and Its Active Compound P-Coumaric Acid Promote Brain-Derived Neurotrophic Factor Signaling for Inducing Hippocampal Neurogenesis and Improving Post-cerebral Ischemic Spatial Cognitive Functions |
| Dandelion | 📋 | ✍ | ⛔ | | 31851841 | Taraxasterol protects hippocampal neurons from oxygen-glucose deprivation-induced injury through activation of Nrf2 signalling pathway |
| Dioscin | 📋 | | | | 34785142 | Dioscin ameliorates diabetes cognitive dysfunction via adjusting P2X7R/NLRP3 signal |
| Diosmetin | 📋 | | | | 35191607 | Diosmetin alleviates cerebral ischemia-reperfusion injury through Keap1-mediated Nrf2/ARE signaling pathway activation and NLRP3 inflammasome inhibition |
| Diosmin | 📋 | ✍ | ⛔ | | 25944567 | Effects of Citrus Flavonoids Against Microvascular Damage Induced by Hypoperfusion and Reperfusion in Rat Pial Circulation |
| Echinacoside | 📋 | | | | 38569512 | Beneficial effects of Echinacoside on cognitive impairment and diabetes in type 2 diabetic db/db mice |
| Equol | 📋 | ✍ | ⛔ | | 34157864 | Roles of Phytoestrogen in the Pathophysiology of Intracranial Aneurysm |
| Fenugreek | 📋 | ✍ | ⛔ | | 31326961 | Fenugreek Seed Extract Ameliorates Cognitive Deficits in Streptozotocin-Induced Diabetic Rats |
| Fucoxanthin | 📋 | ✍ | ⛔ | | 32876840 | Fucoxanthin Mitigates Subarachnoid Hemorrhage-Induced Oxidative Damage via Sirtuin 1-Dependent Pathway |
| Galangal | 📋 | ✍ | ⛔ | | 34419138 | Alpinia oxyphylla Miq extract reduces cerebral infarction by downregulating JNK-mediated TLR4/T3JAM- and ASK1-related inflammatory signaling in the acute phase of transient focal cerebral ischemia in rats |
| Garlic | 📋 | ✍ | ⛔ | | 38136245 | Antioxidant and Anti-Inflammatory Effects of Garlic in Ischemic Stroke: Proposal of a New Mechanism of Protection through Regulation of Neuroplasticity |
| Ginger extract | 📋 | ✍ | ⛔ | | 34679261 | Zingiber officinale (Ginger) hydroalcoholic extract improved avoidance memory in rat model of streptozotocin-induced diabetes by regulating brain oxidative stress |
| Green Tea Polyphenols | 📋 | ✍ | ⛔ | | 23870286 | Green tea polyphenols alleviate early BBB damage during experimental focal cerebral ischemia through regulating tight junctions and PKCalpha signaling |
| Guggulsterone | 📋 | | | | 37230158 | Novel synergistic mechanism of 11-keto-β-boswellic acid and Z-Guggulsterone on ischemic stroke revealed by single-cell transcriptomics |
| Haritaki | 📋 | ✍ | ⛔ | | 38329710 | Evaluation of the biological efficiency of Terminalia chebula fruit extract against neurochemical changes induced in brain of diabetic rats: an epigenetic study |
| Hesperetin | 📋 | | | | 35965833 | Research progress on the mechanism of action of hesperetin in cerebral ischemia: a narrative review |
| Irisin | 📋 | | | | 37466380 | Nattokinase Promotes Post-stroke Neurogenesis and Cognition Recovery via Increasing Circulating Irisin |
| Kudzu Root | 📋 | ✍ | ⛔ | | 36330645 | Research on the material basis and mechanism of Kudzu root in preventing and treating cerebral ischemia based on network pharmacology |
| Moringa Oleifera | 📋 | ✍ | ⛔ | | 31039389 | Moringa oleifera seed extract protects against brain damage in both the acute and delayed stages of ischemic stroke |
| Mulberry | 📋 | | ⛔ | | 32802263 | Memory-Enhancing Effect of a Phytosome Containing the Combined Extract of Mulberry Fruit and Ginger in an Animal Model of Ischemic Stroke with Metabolic Syndrome |
| Myricetin | 📋 | | ⛔ | | 36611117 | Myricetin improves apoptosis after ischemic stroke via inhibiting MAPK-ERK pathway |
| Neohesperidin | 📋 | | | | 23952707 | Neohesperidin attenuates cerebral ischemia-reperfusion injury via inhibiting the apoptotic pathway and activating the Akt/Nrf2/HO-1 pathway |
| Nicotinamide | 📋 | ✍ | ⛔ | | 37626642 | Nicotinamide Deteriorates Post-Stroke Immunodepression Following Cerebral Ischemia-Reperfusion Injury in Mice |
| Persimmon | 📋 | | ⛔ | | 37115470 | Therapeutic effects of a standardized-flavonoid Diospyros kaki L.f. leaf extract on transient focal cerebral ischemia-induced brain injury in mice |
| Pomegranate Peel extract | 📋 | ✍ | ⛔ | | 29433376 | Pomegranate supplementation improves cognitive and functional recovery following ischemic stroke: A randomized trial |
| Pregnenolone | 📋 | ✍ | ⛔ | | 35721911 | Pregnenolone Attenuates the Ischemia-Induced Neurological Deficit in the Transient Middle Cerebral Artery Occlusion Model of Rats |
| Punicalagin | 📋 | ✍ | ⛔ | | 25555468 | Punicalagin attenuated cerebral ischemia-reperfusion insult via inhibition of proinflammatory cytokines, up-regulation of Bcl-2, down-regulation of Bax, and caspase-3 |
| Red Yeast Rice | 📋 | ✍ | ⛔ | | 36306000 | Suppressive role of lovastatin in intracerebral hemorrhage through repression of autophagy |
| Rhodiola | 📋 | ✍ | ⛔ | | 34803686 | Preclinical Evidence and Possible Mechanisms of Rhodiola rosea L. and Its Components for Ischemic Stroke: A Systematic Review and Meta-Analysis |
| Roselle | 📋 | ✍ | ⛔ | | 38193451 | An extract of Hibiscus sabdariffa improves short-term memory in rats with experimental diabetic hyperglycemia |
| Schisandra | 📋 | ✍ | ⛔ | | 35235758 | Gomisin J attenuates cerebral ischemia/reperfusion injury by inducing anti-apoptotic, anti-inflammatory, and antioxidant effects in rats |
| Shogaol | 📋 | | | | 34466075 | Shogaol potentiates sevoflurane mediated neuroprotection against ischemia/reperfusion-induced brain injury via regulating apoptotic proteins and PI3K/Akt/mTOR/s6K signalling and HIF-1α/HO-1 expression |
| Silymarin | 📋 | ✍ | ⛔ | | 32180584 | Comparison of the Effects of Thymoquinone and Silymarin on the Brain of Rats Having Ischemia-Reperfusion in the Lower Extremities |
| Skullcap | 📋 | ✍ | ⛔ | | 37855354 | Network Pharmacology and Molecular Docking Analysis on Mechanisms of Scutellariae Radix in the Treatment of Cerebral Ischemia-reperfusion Injury |
| Stigmasterol | 📋 | | | | 33285471 | The potential LXRβ agonist stigmasterol protects against hypoxia/reoxygenation injury by modulating mitophagy in primary hippocampal neurons |
| Strawberry | 📋 | ✍ | ⛔ | | 32792939 | Strawberry Leaf Extract Treatment Alleviates Cognitive Impairment by Activating Nrf2/HO-1 Signaling in Rats With Streptozotocin-Induced Diabetes |
| Tea Polyphenols | 📋 | | | | 38286317 | Targeting ERS-mitophagy in hippocampal neurons to explore the improvement of memory by tea polyphenols in aged type 2 diabetic rats |
| Theaflavins | 📋 | ✍ | | | 31638230 | Theaflavin attenuates cerebral ischemia/reperfusion injury by abolishing miRNA‑128‑3p‑mediated Nrf2 inhibition and reducing oxidative stress |
| Vitamin B Complex | 📋 | | ⛔ | | 35748292 | Problem in the Recent American Heart Association Guideline on Secondary Stroke Prevention: B Vitamins to Lower Homocysteine Do Prevent Stroke |
| Walnut | 📋 | | ⛔ | | 36014555 | Walnut Prevents Cognitive Impairment by Regulating the Synaptic and Mitochondrial Dysfunction via JNK Signaling and Apoptosis Pathway in High-Fat Diet-Induced C57BL/6 Mice |
| Withaferin A | 📋 | | | | 36453416 | Withaferin A inhibits ferroptosis and protects against intracerebral hemorrhage |
| 5-HTP | 📋 | ✍ | ⛔ | | 37421347 | Effects of adjuvant berberine therapy on acute ischemic stroke: A meta-analysis |
| Alpha GPC | 📋 | ✍ | ⛔ | | 36212684 | Effects of choline containing phospholipids on the neurovascular unit: A review |
| Anethole | 📋 | | | | 36986541 | Anethole Pretreatment Modulates Cerebral Ischemia/Reperfusion: The Role of JNK, p38, MMP-2 and MMP-9 Pathways |
| Anise | 📋 | ✍ | ⛔ | | 37727035 | Protective effects of anise in prevention of cerebral ischemia reperfusion injury in rats |
| Apple | 📋 | | ⛔ | | 23294925 | Total and specific fruit and vegetable consumption and risk of stroke: a prospective study |
| Apple Polyphenols | 📋 | | ⛔ | | 36755790 | Effects of physical exercise associated with a diet enriched with natural antioxidants on cerebral hypoperfusion and reperfusion injury in spontaneously hypertensive rats |
| Arachidonic Acid | 📋 | ✍ | ⛔ | | 29233001 | Arachidonic acid attenuates brain damage in a rat model of ischemia/reperfusion by inhibiting inflammatory response and oxidative stress |
| Arjuna | 📋 | ✍ | ⛔ | | 36234986 | Neuroprotective Effect of Polyphenol Extracts from Terminalia chebula Retz. against Cerebral Ischemia-Reperfusion Injury |
| Asafoetida | 📋 | ✍ | ⛔ | | 38520834 | Kellerin alleviates cerebral ischemic injury by inhibiting ferroptosis via targeting Akt-mediated transcriptional activation of Nrf2 |
| Astragalin | 📋 | | | | 33000226 | Astragalin alleviates ischemia/reperfusion‑induced brain injury via suppression of endoplasmic reticulum stress |
| Avocado Oil | 📋 | | ⛔ | | 26180820 | Avocado Oil Improves Mitochondrial Function and Decreases Oxidative Stress in Brain of Diabetic Rats |
| Balloon Flower | 📋 | ✍ | ⛔ | | 38491972 | Platycodin D Ameliorates Cognitive Impairment in Type 2 Diabetes Mellitus Mice via Regulating PI3K/Akt/GSK3β Signaling Pathway |
| Bay Leaf | 📋 | | ⛔ | | 20944422 | Amelioration of oxygen and glucose deprivation-induced neuronal death by chloroform fraction of bay leaves (Laurus nobilis) |
| Bergamot | 📋 | ✍ | ⛔ | | 18413898 | The protective effect of bergamot oil extract on lecitine-like oxyLDL receptor-1 expression in balloon injury-related neointima formation |
| Bergamot Essential Oil | 📋 | ✍ | ⛔ | | 19607983 | Prevention of Glutamate Accumulation and Upregulation of Phospho-Akt may Account for Neuroprotection Afforded by Bergamot Essential Oil against Brain Injury Induced by Focal Cerebral Ischemia in Rat |
| Beta-Alanine | 📋 | ✍ | ⛔ | | 36038575 | Multi-target action of β-alanine protects cerebellar tissue from ischemic damage |
| Beta-Sitosterol | 📋 | ✍ | ⛔ | | 37721296 | Treatment with β-sitosterol ameliorates the effects of cerebral ischemia/reperfusion injury by suppressing cholesterol overload, endoplasmic reticulum stress, and apoptosis |
| Betaine | 📋 | ✍ | ⛔ | | 35020521 | Betaine Ameliorates Brain Damage in a Rat Model of Ischemia/Reperfusion Injury |
| Betulinic Acid | 📋 | | | | 34296845 | Betulinic Acid Ameliorates Cerebral Injury in Middle Cerebral Artery Occlusion Rats through Regulating Autophagy |
| Bilberry | 📋 | ✍ | ⛔ | | 28865231 | Effect of feeding with bilberry fruit on the expression pattern of αCaMKII in hippocampal neurons in normal and diabetic rats |
| Biochanin A | 📋 | | | | 34322090 | Biochanin A Alleviates Cerebral Ischemia/Reperfusion Injury by Suppressing Endoplasmic Reticulum Stress-Induced Apoptosis and p38MAPK Signaling Pathway In Vivo and In Vitro |
| Black Pepper Essential Oil | 📋 | | ⛔ | | 25642050 | The effect of olfactory stimuli on the balance ability of stroke patients |
| Blackberry | 📋 | | ⛔ | | 37743615 | Rubus fruticosus leaf extract inhibits vascular dementia-induced memory impairment and neuronal loss by attenuating neuroinflammation |
| Blueberry | 📋 | ✍ | ⛔ | | 34580912 | Neuroprotective effect of wild lowbush blueberry (Vaccinium angustifolium) on global cerebral ischemia/reperfusion injury in rats: Downregulation of iNOS/TNF-α and upregulation of miR-146a/miR-21 expression |
| Bread | 📋 | | | | 38528644 | Sourdough bread as nutritional intervention tool for improvement of cognitive dysfunction in diabetic rats |
| Camellia | 📋 | | ⛔ | | 30758441 | Protective effect of extract of the Camellia japonica L. on cerebral ischemia-reperfusion injury in rats |
| Cardamom | 📋 | ✍ | ⛔ | | 30539783 | Terpenoid-rich Elettaria cardamomum extract prevents Alzheimer-like alterations induced in diabetic rats via inhibition of GSK3β activity, oxidative stress and pro-inflammatory cytokines |
| Cardamonin | 📋 | | | | 35142404 | Cardamonin attenuates cerebral ischemia/reperfusion injury by activating the HIF-1α/VEGFA pathway |
| Carnosic Acid | 📋 | | | | 30890904 | Carnosic Acid Mitigates Early Brain Injury After Subarachnoid Hemorrhage: Possible Involvement of the SIRT1/p66shc Signaling Pathway |
| Casein Protein | 📋 | ✍ | ⛔ | | 35928572 | Casein kinase 2 attenuates brain injury induced by intracerebral hemorrhage via regulation of NR2B phosphorylation |
| Catechins | 📋 | | | | 16443357 | Mechanisms of action of green tea catechins, with a focus on ischemia-induced neurodegeneration |
| Chamomile | 📋 | ✍ | ⛔ | | 36302045 | Ameliorative effects of half-dose saffron and chamomile combination on Psycho-endocrinological changes in a diabetic murine model |
| Cheese | 📋 | | ⛔ | | 35889893 | Effect of Cheese Intake on Cardiovascular Diseases and Cardiovascular Biomarkers |
| Chlorella | 📋 | ✍ | ⛔ | | 17330510 | Effect of chlorella and its fractions on blood pressure, cerebral stroke lesions, and life-span in stroke-prone spontaneously hypertensive rats |
| Choline | 📋 | ✍ | ⛔ | | 36212684 | Effects of choline containing phospholipids on the neurovascular unit: A review |
| Chondroitin | 📋 | ✍ | ⛔ | | 35923649 | Risk of ischaemic stroke among new users of glucosamine and chondroitin sulphate: a nested case-control study |
| Cinnamaldehyde | 📋 | | | | 31444631 | The effects of Cinnamaldehyde on early brain injury and cerebral vasospasm following experimental subarachnoid hemorrhage in rabbits |
| Citrus Fruits | 📋 | | ⛔ | | 34266770 | Poncirin ameliorates oxygen glucose deprivation/reperfusion injury in cortical neurons via inhibiting NOX4-mediated NLRP3 inflammasome activation |
| Coconut Oil | 📋 | | ⛔ | | 36430992 | Favorable Effects of Virgin Coconut Oil on Neuronal Damage and Mortality after a Stroke Incidence in the Stroke-Prone Spontaneously Hypertensive Rat |
| Coptis Chinensis | 📋 | | ⛔ | | 30214157 | The total alkaloids from Coptis chinensis Franch improve cognitive deficits in type 2 diabetic rats |
| Cordyceps | 📋 | ✍ | ⛔ | | 31978767 | The protective effect of cordyceps sinensis extract on cerebral ischemic injury via modulating the mitochondrial respiratory chain and inhibiting the mitochondrial apoptotic pathway |
| Corn Silk | 📋 | ✍ | ⛔ | | 35052672 | Protection against Neurological Symptoms by Consuming Corn Silk Water Extract in Artery-Occluded Gerbils with Reducing Oxidative Stress, Inflammation, and Post-Stroke Hyperglycemia through the Gut-Brain Axis |
| Cryptotanshinone | 📋 | | | | 33915069 | Cryptotanshinone possesses therapeutic effects on ischaemic stroke through regulating STAT5 in a rat model |
| Date | 📋 | | ⛔ | | 21870431 | Evaluation of antioxidant and neuroprotective effect of date palm (Phoenix dactylifera L.) against bilateral common carotid artery occlusion in rats |
| DHEA | 📋 | ✍ | ⛔ | | 34482541 | Neurosteroids: A novel promise for the treatment of stroke and post-stroke complications |
| Dihydroartemisinin | 📋 | | | | 37415610 | Dihydroartemisinin ameliorates cerebral I/R injury in rats via regulating VWF and autophagy-mediated SIRT1/FOXO1 pathway |
| DIM | 📋 | ✍ | ⛔ | | 35440324 | Neuroprotective effect of 3,3'-diindolylmethane and É‘-naphthoflavone, aryl hydrocarbon receptor modulators in an experimental model of ischemic stroke |
| Eclipta Alba | 📋 | ✍ | | | 38562322 | Investigation of the Cognitive Activity Between the Leaf Extracts of Eclipta alba and Ziziphus jujuba in Diabetic Animal Models |
| Eleuthero | 📋 | ✍ | ⛔ | | 37518502 | Therapeutic effect of Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. leaves on ischemic stroke via the microbiota-gut-brain axis |
| Essential Amino Acids | 📋 | ✍ | ⛔ | | 37397466 | A balanced formula of essential amino acids promotes brain mitochondrial biogenesis and protects neurons from ischemic insult |
| Essential Oils | 📋 | | ⛔ | | 35659628 | Natural essential oils: A promising strategy for treating cardio-cerebrovascular diseases |
| Eucalyptol | 📋 | | | | 33550883 | Eucalyptol ameliorates early brain injury after subarachnoid haemorrhage via antioxidant and anti-inflammatory effects in a rat model |
| Eucalyptus | 📋 | ✍ | ⛔ | | 33562701 | Study of Neuroprotection by a Combination of the Biological Antioxidant ( Eucalyptus Extract) and the Antihypertensive Drug Candesartan against Chronic Cerebral Ischemia in Rats |
| Eugenol | 📋 | | | | 32153404 | Eugenol Attenuates Cerebral Ischemia-Reperfusion Injury by Enhancing Autophagy via AMPK-mTOR-P70S6K Pathway |
| Fiber | 📋 | ✍ | ⛔ | | 37196565 | The relationship between dietary fibre and stroke: A meta-analysis |
| Fufang Danshen | 📋 | | | | 34107328 | Chemical composition, quality control, pharmacokinetics, pharmacological properties and clinical applications of Fufang Danshen Tablet: A systematic review |
| Genipin | 📋 | | | | 36670935 | Genipin Attenuates Diabetic Cognitive Impairment by Reducing Lipid Accumulation and Promoting Mitochondrial Fusion via FABP4/Mfn1 Signaling in Microglia |
| Geraniin | 📋 | | | | 35222793 | Geraniin Protects against Cerebral Ischemia/Reperfusion Injury by Suppressing Oxidative Stress and Neuronal Apoptosis via Regulation of the Nrf2/HO-1 Pathway |
| Grapefruit extract | 📋 | ✍ | ⛔ | | 37283121 | Flavonoids from Citrus paradise cv. Changshan-huyou exerts protective effect on ischemia-induced cerebral injury in mice via inhibiting RhoA-ROCK2 signaling pathway |
| Hawthorn | 📋 | ✍ | ⛔ | | 31720488 | Effect of Crataegus extract supplementation on diabetes induced memory deficits and serum biochemical parameters in male rats |
| Honey | 📋 | ✍ | ⛔ | | 32774089 | Morphometric Analysis of the Effects of Manuka Honey on Vasospastic Femoral Arteries in Rats: An Experimental Study |
| Hyaluronic Acid | 📋 | ✍ | ⛔ | | 32213158 | Hyaluronic Acid and Regenerative Medicine: New Insights Into the Stroke Therapy |
| Indian Gooseberry | 📋 | | ⛔ | | 35674296 | Phyllanthus emblica L. regulates BDNF/PI3K pathway to modulate glutathione towards mitoprotection and neuroprotection in a rodent model of ischemic stroke |
| Iron | 📋 | ✍ | ⛔ | | 18988909 | Is ischemic stroke risk related to folate status or other nutrients correlated with folate intake? |
| Jujube | 📋 | | ⛔ | | 38562322 | Investigation of the Cognitive Activity Between the Leaf Extracts of Eclipta alba and Ziziphus jujuba in Diabetic Animal Models |
| Kombucha | 📋 | ✍ | ⛔ | | 37402035 | Chronic Kombucha Beverage Consumption Attenuates Inflammatory Markers and Histopathology of Brain Tissue in Transnet Global Brain Ischemia in Rats |
| L-Alanine | 📋 | ✍ | ⛔ | | 33626855 | Extremely Low Serum Alanine Transaminase Level Is Associated with All-Cause Mortality in the Elderly after Intracranial Hemorrhage |
| L-Arginine | 📋 | ✍ | ⛔ | | 14724366 | L-arginine Improves Cerebral Blood Perfusion and Vasomotion of Microvessels Following Subarachnoid Hemorrhage in Rats |
| L-Glutamine | 📋 | ✍ | ⛔ | | 36605307 | Investigating the protective effect of glutamine against cerebral ischemia and bilateral carotid occlusion in rats |
| L-Leucine | 📋 | ✍ | ⛔ | | 37891741 | Leucine Reduced Blood-Brain Barrier Disruption and Infarct Size in Early Cerebral Ischemia-Reperfusion |
| L-Lysine | 📋 | ✍ | ⛔ | | 10416829 | Neuroprotective Effect of L-lysine Monohydrochloride on Acute Iterative Anoxia in Rats With Quantitative Analysis of Electrocorticogram |
| L-Theanine | 📋 | ✍ | ⛔ | | 25977676 | Can Tea Consumption be a Safe and Effective Therapy Against Diabetes Mellitus-Induced Neurodegeneration? |
| Lactobacillus plantarum | 📋 | | ⛔ | | 27144579 | Effects of Lactobacillus plantarum TWK10-Fermented Soymilk on Deoxycorticosterone Acetate-Salt-Induced Hypertension and Associated Dementia in Rats |
| Lauric Acid | 📋 | ✍ | | | 37572940 | Lauric acid provides neuroprotection against oxidative stress in mouse model of hyperglycaemic stroke |
| Lavender Essential Oil | 📋 | ✍ | ⛔ | | 25642050 | The effect of olfactory stimuli on the balance ability of stroke patients |
| Lemon Balm | 📋 | ✍ | ⛔ | | 34004260 | The effect of Melissa officinalis L. extract on learning and memory: involvement of hippocampal expression of nitric oxide synthase and brain-derived neurotrophic factor in diabetic rats |
| Lingonberry | 📋 | | ⛔ | | 25941748 | Partridgeberry polyphenols protect rat primary cortical neurons from oxygen-glucose deprivation-reperfusion-induced injury via suppression of inflammatory adipokines and regulation of HIF-1α and PPARγ |
| Lutein | 📋 | ✍ | ⛔ | | 32750510 | Effects of lutein on brain damage and vasospasm in the experimental subarachnoid hemorrhage model |
| Malvidin | 📋 | | | | 36699054 | Malvidin alleviates mitochondrial dysfunction and ROS accumulation through activating AMPK-α/UCP2 axis, thereby resisting inflammation and apoptosis in SAE mice |
| Mango Leaf | 📋 | | ⛔ | | 27537110 | Mango leaf extract improves central pathology and cognitive impairment in a type 2 diabetes mouse model |
| Mangosteen | 📋 | ✍ | ⛔ | | 32743849 | Xanthone-enriched fraction of Garcinia mangostana and α-mangostin improve the spatial learning and memory of chronic cerebral hypoperfusion rats |
| Marigold | 📋 | ✍ | ⛔ | | 26120230 | Effect of Calendula officinalis hydroalcoholic extract on passive avoidance learning and memory in streptozotocin-induced diabetic rats |
| Micronutrients | 📋 | | ⛔ | | 37764713 | Key Nutrients for Optimal Blood Glucose Control and Mental Health in Individuals with Diabetes: A Review of the Evidence |
| Morin | 📋 | | | | 35857717 | Morin and isoquercitrin protect against ischemic neuronal injury by modulating signaling pathways and stimulating mitochondrial biogenesis |
| Mucuna Pruriens | 📋 | ✍ | ⛔ | | 36875022 | Effect of Mucuna pruriens on brain NMDA receptor and tau protein gene expression in cerebral ischemic rats |
| Myrrh | 📋 | ✍ | ⛔ | | 35082676 | Combination of Systems Pharmacology and Experimental Evaluation to Explore the Mechanism of Synergistic Action of Frankincense-Myrrh in the Treatment of Cerebrovascular Diseases |
| NAD | 📋 | | | | 34530866 | NAD + improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway |
| Nuts | 📋 | | ⛔ | | 34578913 | Association of Nut Consumption with Risk of Stroke and Cardiovascular Disease: The Million Veteran Program |
| Oleanolic Acid | 📋 | | | | 35056059 | Oleanolic Acid Alleviates Cerebral Ischemia/Reperfusion Injury via Regulation of the GSK-3β/HO-1 Signaling Pathway |
| Oleic Acid | 📋 | | ⛔ | | 21676914 | Olive oil consumption, plasma oleic acid, and stroke incidence: the Three-City Study |
| Olive Polyphenols | 📋 | | | | 36364796 | Neuroprotective Panel of Olive Polyphenols: Mechanisms of Action, Anti-Demyelination, and Anti-Stroke Properties |
| Omega-6 Fatty Acids | 📋 | ✍ | ⛔ | | 37971997 | Association between the intake of dietary n3 and n6 fatty acids and stroke in US adults: A cross-sectional study of NHANES 2007-2018 |
| Oolong Tea | 📋 | | ⛔ | | 19478218 | Tea Consumption and Ischemic Stroke Risk: A Case-Control Study in Southern China |
| Paeonol | 📋 | | | | 33906483 | Paeonol inhibits the progression of intracerebral haemorrhage by mediating the HOTAIR/UPF1/ACSL4 axis |
| Parthenolide | 📋 | | | | 35947899 | Parthenolide modulates cerebral ischemia-induced microglial polarization and alleviates neuroinflammatory injury via the RhoA/ROCK pathway |
| Patchouli | 📋 | ✍ | ⛔ | | 30988709 | Effect of β-patchoulene on cerebral ischemia-reperfusion injury and the TLR4/NF-κB signaling pathway |
| Pear | 📋 | | ⛔ | | 23294925 | Total and specific fruit and vegetable consumption and risk of stroke: a prospective study |
| Pelargonidin | 📋 | | | | 33552591 | Pelargonidin ameliorates MCAO-induced cerebral ischemia/reperfusion injury in rats by the action on the Nrf2/HO-1 pathway |
| Perilla | 📋 | ✍ | | | 35723398 | Perilla frutescens Leaf Extract Attenuates Vascular Dementia-Associated Memory Deficits, Neuronal Damages, and Microglial Activation |
| Phytoestrogens | 📋 | | ⛔ | | 32580379 | Neuroprotection by Phytoestrogens in the Model of Deprivation and Resupply of Oxygen and Glucose In Vitro: The Contribution of Autophagy and Related Signaling Mechanisms |
| Pistachio | 📋 | ✍ | ⛔ | | 35075081 | Chronically Pre-treatment of Pistachio Alters the Morphology of CA1 Hippocampus Neurons Following Transient Focal Cerebral Ischemia in Male Wistar Rats |
| Proanthocyanidins | 📋 | | | | 37096349 | Proanthocyanidins may be potential therapeutic agents for the treatment of carotid atherosclerosis: A review |
| Procyanidins | 📋 | | ⛔ | | 37110816 | Procyanidins Alleviated Cerebral Ischemia/Reperfusion Injury by Inhibiting Ferroptosis via the Nrf2/HO-1 Signaling Pathway |
| Prunella Vulgaris | 📋 | ✍ | ⛔ | | 35678758 | Vulgarisin-type diterpenoids from self-heal ( Prunella vulgaris) and their neuroprotective effects against ischemia/reperfusion (I/R) via a mitochondria-related pathway |
| Psyllium | 📋 | ✍ | ⛔ | | 31103857 | Intake of Psyllium Seed Husk Reduces White Matter Damage in a Rat Model of Chronic Cerebral Hypoperfusion |
| PUFA | 📋 | | | | 32717402 | Polyunsaturated fatty acid supplement alleviates depression-incident cognitive dysfunction by protecting the cerebrovascular and glymphatic systems |
| Rehmannia | 📋 | ✍ | ⛔ | | 35091012 | Rehmannioside A improves cognitive impairment and alleviates ferroptosis via activating PI3K/AKT/Nrf2 and SLC7A11/GPX4 signaling pathway after ischemia |
| Rosavin | 📋 | | ⛔ | | 37254848 | Rosavin protects the blood-brain barrier against ischemia/reperfusion-induced cerebral injury by regulating MAPK-mediated MMPs pathway |
| Rosehip | 📋 | ✍ | ⛔ | | 37088237 | Rosa canina L. improves learning and memory-associated cognitive impairment by regulating glucose levels and reducing hippocampal insulin resistance in high-fat diet/streptozotocin-induced diabetic rats |
| Safranal | 📋 | | | | 38234630 | Safranal acts as a neurorestorative agent in rats with cerebral ischemic stroke via upregulating SIRT1 |
| Salt | 📋 | | ⛔ | | 35788204 | Role of no table salt on hypertension and stroke based on large sample size from National Health and Nutrition Examination Survey database |
| Seaweeds | 📋 | | ⛔ | | 37405739 | Neuroprotective Potential of Brown Seaweed Phytochemicals in Rodent Models of Cerebral Ischemia |
| Senolytics | 📋 | | | | 35763058 | Brain Cell Senescence: A New Therapeutic Target for the Acute Treatment of Ischemic Stroke |
| Sesamin | 📋 | ✍ | | | 33440305 | Sesamin alleviates diabetes-associated behavioral deficits in rats: The role of inflammatory and neurotrophic factors |
| Sesamol | 📋 | | | | 37848698 | Sesamol defends neuronal damage following cerebral ischemia/reperfusion: a crosstalk of autophagy and Notch1/NLRP3 inflammasome signaling |
| Soy Isoflavones | 📋 | ✍ | ⛔ | | 36946055 | [Soybean isoflavones alleviate cerebral ischemia/reperfusion injury in rats by inhibiting ferroptosis and inflammatory cascade reaction] |
| Spermidine | 📋 | | | | 36367791 | Spermidine inhibits high glucose-induced endoplasmic reticulum stress in HT22 cells by upregulation of growth differentiation factor 11 |
| Spikenard | 📋 | ✍ | ⛔ | | 12479970 | Protective effect of Nardostachys jatamansi in rat cerebral ischemia |
| St. Johns Wort | 📋 | ✍ | ⛔ | | 27328426 | Hyperforin Promotes Post-Stroke Functional Recovery Through Interleukin (IL)-17A-mediated Angiogenesis |
| Sunflower Oil | 📋 | ✍ | ⛔ | | 33749789 | Systemic administration of sunflower oil exerts neuroprotection in a mouse model of transient focal cerebral ischaemia |
| Tangerine | 📋 | | ⛔ | | 35100035 | Effects of Citrus depressa Hayata Fruit Extract on Thigh Muscles Mass and Composition in Subacute Stroke Patients: A Double-Blind, Randomized, Controlled Pilot Trial |
| Tannic Acid | 📋 | ✍ | ⛔ | | 34562517 | Tannic acid protects aged brain against cerebral hypoperfusion via modulation of Nrf2 and inflammatory pathways |
| Tetrahydrocurcumin | 📋 | ✍ | | | 27748926 | Suppression of GRASP65 Phosphorylation by Tetrahydrocurcumin Protects Against Cerebral Ischemia/Reperfusion Injury via ERK Signaling |
| Trans-Resveratrol | 📋 | | | | 35799401 | Neuroprotection by Trans-Resveratrol in Rats With Intracerebral Hemorrhage: Insights into the Role of Adenosine A1 Receptors |
| UDCA | 📋 | ✍ | ⛔ | | 37989444 | Gut microbiota-mediated ursodeoxycholic acids regulate the inflammation of microglia through TGR5 signaling after MCAO |
| Ursolic Acid | 📋 | ✍ | ⛔ | | 37834220 | Ursolic Acid Alleviates Neuroinflammation after Intracerebral Hemorrhage by Mediating Microglial Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway |
| Valerian Root | 📋 | ✍ | ⛔ | | 25785762 | Valeriana officinalis Extracts Ameliorate Neuronal Damage by Suppressing Lipid Peroxidation in the Gerbil Hippocampus Following Transient Cerebral Ischemia |
| Vitamin B2 | 📋 | ✍ | ⛔ | | 18988909 | Is ischemic stroke risk related to folate status or other nutrients correlated with folate intake? |
| Vitamin K | 📋 | ✍ | ⛔ | | 33036224 | Vitamin K Intake in Chronic Stroke: Implications for Dietary Recommendations |
| Vitamin K1 | 📋 | ✍ | ⛔ | | 35660920 | Inverse association between plasma phylloquinone and risk of ischemic stroke in Chinese adults with hypertension and high body mass index: a nested case-control study |
| Vitamin K2 | 📋 | ✍ | ⛔ | | 33546354 | Doppler Ultrasound Monitoring of Echogenicity in Asymptomatic Subcritical Carotid Stenosis and Assessment of Response to Oral Supplementation of Vitamin K2 (PLAK2 Randomized Controlled Trial) |
| Vitamin K2 mk-7 | 📋 | ✍ | | | 33090426 | Menaquinone-7 protects astrocytes by regulating mitochondrial function and inflammatory response under hypoxic conditions |
| Vitamins | 📋 | | | | 38291560 | From A to E: Uniting vitamins against stroke risk-A systematic review and network meta-analysis |
| Yam | 📋 | | | | 35777608 | Study on the pharmacodynamic effect of Rhizoma Dioscoreae polysaccharides on cerebral ischemia-reperfusion injury in rats and the possible mechanism |
| Yogurt | 📋 | | ⛔ | | 38053820 | Association of milk and dairy product consumption with the incidence of cardio-cerebrovascular disease incidence in middle-aged and older Korean adults: a 16-year follow-up of the Korean Genome and Epidemiology Study |
| Zeaxanthin | 📋 | ✍ | ⛔ | | 28599877 | Zeaxanthin improves diabetes-induced cognitive deficit in rats through activiting PI3K/AKT signaling pathway |
